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The Liebeskind-Srogl cross-coupling reaction towards the synthesis of biologically active compounds
J. Chasák, I. Janicki, L. Brulíková
Jazyk angličtina Země Francie
Typ dokumentu časopisecké články, přehledy
- MeSH
- katalýza MeSH
- kyseliny boronové * chemie MeSH
- molekulární struktura MeSH
- palladium chemie MeSH
- techniky syntetické chemie * metody MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
In this review, we emphasize the significance of the Liebeskind-Srogl cross-coupling reaction, a palladium-catalyzed process involving the reaction between a thioester and a boronic acid. This reaction has emerged as a fundamental technique in synthetic methodologies aimed at the development of biologically active compounds. The Liebeskind-Srogl cross-coupling method has become an essential approach in chemistry, facilitating the diversification of complex structures that would be significantly more challenging to synthesize through alternative approaches. In this review, we aim to outline the numerous possibilities for preparing a wide range of derivatives, each with notable biological potential.
Citace poskytuje Crossref.org
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- $a Chasák, Jan $u Department of Organic Chemistry, Faculty of Science, Palacký University, 17. listopadu 12, 77146, Olomouc, Czech Republic
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- $a In this review, we emphasize the significance of the Liebeskind-Srogl cross-coupling reaction, a palladium-catalyzed process involving the reaction between a thioester and a boronic acid. This reaction has emerged as a fundamental technique in synthetic methodologies aimed at the development of biologically active compounds. The Liebeskind-Srogl cross-coupling method has become an essential approach in chemistry, facilitating the diversification of complex structures that would be significantly more challenging to synthesize through alternative approaches. In this review, we aim to outline the numerous possibilities for preparing a wide range of derivatives, each with notable biological potential.
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