-
Something wrong with this record ?
Excess mortality in people hospitalised for alcohol use disorders before and during the pandemic - A registry-based retrospective cohort study
L. Kážmér, O. Šíba, B. Orlíková
Language English Country Australia
Document type Journal Article
Grant support
CZ.02.01.01/00/22_008/0004583
Ministry of Education, Youth and Sports of the Czech Republic, the Operational Programme Johannes Amos Comenius (OP JAC)
NU22-D-146
Agentura pro zdravotnický výzkum České Republiky
PubMed
40134124
DOI
10.1111/dar.14045
Knihovny.cz E-resources
- MeSH
- Alcoholism * mortality MeSH
- COVID-19 * epidemiology MeSH
- Adult MeSH
- Hospitalization * trends statistics & numerical data MeSH
- Cohort Studies MeSH
- Middle Aged MeSH
- Humans MeSH
- Young Adult MeSH
- Life Expectancy * trends MeSH
- Pandemics * MeSH
- Alcohol-Related Disorders * mortality MeSH
- Registries MeSH
- Retrospective Studies MeSH
- Aged MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Young Adult MeSH
- Male MeSH
- Aged MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Geographicals
- Czech Republic MeSH
INTRODUCTION: The aim was to analyse mortality and estimate the life expectancy among people hospitalised for alcohol use disorders (AUD) compared with the general Czech population aged ≥20 years. A temporal perspective on excess mortality was used, covering three recent calendar periods before and during the pandemic. METHODS: Three retrospective cohorts of the target population were constructed using registry-based data. The target population was defined as all adult patients (aged ≥20 years) admitted to the hospital for AUD (ICD-10 dg. of F10.x) between 2010 and 2021. Age-adjusted mortality rates and life expectancies were calculated for the comparative analysis. Official Czech mortality and vital statistics were used for the comparison. A Poisson log-linear regression model was used to test the effect of the pandemic period (2020-2021) on mortality in the AUD target population. RESULTS: At age 20, the estimated life expectancy of the AUD target was 21-27 years less than that of the Czech general population. Excess mortality was relatively highest in young people aged 20-34 years and in adults aged 35-49 years. During the pandemic period 2020-2021, mortality rates in the target AUD increased significantly. However, relative inequalities with the general Czech population did not change significantly. DISCUSSION AND CONCLUSIONS: People hospitalised for AUD have much higher mortality rates, resulting in markedly reduced life expectancy. During the pandemic, their mortality rates increased even more. However, the increase was no greater than in the general Czech population.
References provided by Crossref.org
- 000
- 00000naa a2200000 a 4500
- 001
- bmc25015892
- 003
- CZ-PrNML
- 005
- 20250731091329.0
- 007
- ta
- 008
- 250708s2025 at f 000 0|eng||
- 009
- AR
- 024 7_
- $a 10.1111/dar.14045 $2 doi
- 035 __
- $a (PubMed)40134124
- 040 __
- $a ABA008 $b cze $d ABA008 $e AACR2
- 041 0_
- $a eng
- 044 __
- $a at
- 100 1_
- $a Kážmér, Ladislav $u National Institute of Mental Health, Klecany, Czech Republic $1 https://orcid.org/0000000193697721 $7 ola2017963655
- 245 10
- $a Excess mortality in people hospitalised for alcohol use disorders before and during the pandemic - A registry-based retrospective cohort study / $c L. Kážmér, O. Šíba, B. Orlíková
- 520 9_
- $a INTRODUCTION: The aim was to analyse mortality and estimate the life expectancy among people hospitalised for alcohol use disorders (AUD) compared with the general Czech population aged ≥20 years. A temporal perspective on excess mortality was used, covering three recent calendar periods before and during the pandemic. METHODS: Three retrospective cohorts of the target population were constructed using registry-based data. The target population was defined as all adult patients (aged ≥20 years) admitted to the hospital for AUD (ICD-10 dg. of F10.x) between 2010 and 2021. Age-adjusted mortality rates and life expectancies were calculated for the comparative analysis. Official Czech mortality and vital statistics were used for the comparison. A Poisson log-linear regression model was used to test the effect of the pandemic period (2020-2021) on mortality in the AUD target population. RESULTS: At age 20, the estimated life expectancy of the AUD target was 21-27 years less than that of the Czech general population. Excess mortality was relatively highest in young people aged 20-34 years and in adults aged 35-49 years. During the pandemic period 2020-2021, mortality rates in the target AUD increased significantly. However, relative inequalities with the general Czech population did not change significantly. DISCUSSION AND CONCLUSIONS: People hospitalised for AUD have much higher mortality rates, resulting in markedly reduced life expectancy. During the pandemic, their mortality rates increased even more. However, the increase was no greater than in the general Czech population.
- 650 _2
- $a lidé $7 D006801
- 650 _2
- $a dospělí $7 D000328
- 650 _2
- $a retrospektivní studie $7 D012189
- 650 _2
- $a lidé středního věku $7 D008875
- 650 _2
- $a mužské pohlaví $7 D008297
- 650 _2
- $a registrace $7 D012042
- 650 _2
- $a ženské pohlaví $7 D005260
- 650 12
- $a hospitalizace $x trendy $x statistika a číselné údaje $7 D006760
- 650 12
- $a naděje dožití $x trendy $7 D008017
- 650 _2
- $a mladý dospělý $7 D055815
- 650 _2
- $a senioři $7 D000368
- 650 12
- $a COVID-19 $x epidemiologie $7 D000086382
- 650 12
- $a pandemie $7 D058873
- 650 12
- $a poruchy způsobené alkoholem $x mortalita $7 D019973
- 650 12
- $a alkoholismus $x mortalita $7 D000437
- 650 _2
- $a kohortové studie $7 D015331
- 651 _2
- $a Česká republika $x epidemiologie $7 D018153
- 655 _2
- $a časopisecké články $7 D016428
- 700 1_
- $a Šíba, Ondřej $u National Institute of Mental Health, Klecany, Czech Republic $1 https://orcid.org/0009000949894504
- 700 1_
- $a Orlíková, Barbora $u National Institute of Mental Health, Klecany, Czech Republic $1 https://orcid.org/0000000344884787 $7 mzk2006343152
- 773 0_
- $w MED00004925 $t Drug and alcohol review $x 1465-3362 $g Roč. 44, č. 4 (2025), s. 1229-1239
- 856 41
- $u https://pubmed.ncbi.nlm.nih.gov/40134124 $y Pubmed
- 910 __
- $a ABA008 $b sig $c sign $y - $z 0
- 990 __
- $a 20250708 $b ABA008
- 991 __
- $a 20250731091323 $b ABA008
- 999 __
- $a ok $b bmc $g 2366611 $s 1253017
- BAS __
- $a 3
- BAS __
- $a PreBMC-MEDLINE
- BMC __
- $a 2025 $b 44 $c 4 $d 1229-1239 $e 20250325 $i 1465-3362 $m Drug and alcohol review $n Drug Alcohol Rev $x MED00004925
- GRA __
- $a CZ.02.01.01/00/22_008/0004583 $p Ministry of Education, Youth and Sports of the Czech Republic, the Operational Programme Johannes Amos Comenius (OP JAC)
- GRA __
- $a NU22-D-146 $p Agentura pro zdravotnický výzkum České Republiky
- LZP __
- $a Pubmed-20250708