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Promoting Prevention and Targeting Remission of Asthma: A EUFOREA Consensus Statement on Raising the Bar in Asthma Care
M. Jesenak, A. Bobcakova, R. Djukanovic, M. Gaga, NA. Hanania, LG. Heaney, I. Pavord, S. Quirce, D. Ryan, W. Fokkens, D. Conti, PW. Hellings, G. Scadding, E. Van Staeyen, LH. Bjermer, Z. Diamant
Jazyk angličtina
Typ dokumentu konsensus - konference, časopisecké články
- MeSH
- antiastmatika * terapeutické užití MeSH
- bronchiální astma * prevence a kontrola terapie farmakoterapie MeSH
- individualizovaná medicína MeSH
- indukce remise MeSH
- konsensus MeSH
- kvalita života MeSH
- lidé MeSH
- management nemoci MeSH
- progrese nemoci MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- konsensus - konference MeSH
Asthma is a common, multifaceted respiratory disease with a major impact on quality of life. Despite increased insights into mechanisms underlying various asthma phenotypes and endotypes and the availability of targeted biologic treatment options, the disease remains uncontrolled in a substantial proportion of patients with risk of exacerbations, requiring systemic corticosteroids, and with progressive disease. Current international guidelines advocate for a personalized management approach to patients with uncontrolled severe asthma. The European Forum for Research and Education in Allergy and Airway Diseases (EUFOREA) asthma expert panel was convened to discuss strategies to optimize asthma care and to prevent systemic corticosteroid overuse and disease progression. In this meeting report, we summarize current concepts and recommendations and provide a rationale to implement personalized asthma management at earlier stages of the disease. The ultimate goal is to move away from the current one-size-fits-most concept, which focuses on a symptom-driven treatment strategy, and shift toward a phenotype- and endotype-targeted approach aimed at curbing the disease course by improving clinical outcomes and preserving health-related quality of life. Herein, we provide a consensus view on asthma care that advocates a holistic approach and highlight some unmet needs to be addressed in future clinical trials and population studies.
1st Respiratory Medicine Dept Hygeia Hospital Athens Greece
AUKCAR Usher Institute University of Edinburgh Edinburgh United Kingdom
Department of Allergy La Paz University Hospital IdiPAZ CIBER of Respiratory Diseases Madrid Spain
Department of Otorhinolaryngology Amsterdam University Medical Centres Amsterdam the Netherlands
Department of Otorhinolaryngology University of Leuven Leuven Belgium
Division of Infection and Immunity University College London United Kingdom
Laboratory of Allergy and Clinical Immunology University of Leuven Leuven Belgium
NIHR Southampton Biomedical Centre Faculty of Medicine University of Southampton United Kingdom
Section of Pulmonary and Critical Care Medicine Baylor College of Medicine Houston TX
The Royal National ENT Hospital London United Kingdom
Upper Airways Disease Laboratory University of Ghent Ghent Belgium
Citace poskytuje Crossref.org
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- $a Jesenak, Milos $u Department of Pediatrics, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, University Teaching Hospital in Martin, Martin, Slovakia; Department of Pulmonology and Phthisiology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, University Teaching Hospital in Martin, Martin, Slovakia; Institute of Clinical Immunology and Medical Genetics, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, University Teaching Hospital in Martin, Martin, Slovakia
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- $a Asthma is a common, multifaceted respiratory disease with a major impact on quality of life. Despite increased insights into mechanisms underlying various asthma phenotypes and endotypes and the availability of targeted biologic treatment options, the disease remains uncontrolled in a substantial proportion of patients with risk of exacerbations, requiring systemic corticosteroids, and with progressive disease. Current international guidelines advocate for a personalized management approach to patients with uncontrolled severe asthma. The European Forum for Research and Education in Allergy and Airway Diseases (EUFOREA) asthma expert panel was convened to discuss strategies to optimize asthma care and to prevent systemic corticosteroid overuse and disease progression. In this meeting report, we summarize current concepts and recommendations and provide a rationale to implement personalized asthma management at earlier stages of the disease. The ultimate goal is to move away from the current one-size-fits-most concept, which focuses on a symptom-driven treatment strategy, and shift toward a phenotype- and endotype-targeted approach aimed at curbing the disease course by improving clinical outcomes and preserving health-related quality of life. Herein, we provide a consensus view on asthma care that advocates a holistic approach and highlight some unmet needs to be addressed in future clinical trials and population studies.
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- $a Bobcakova, Anna $u Department of Pediatrics, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, University Teaching Hospital in Martin, Martin, Slovakia; Department of Pulmonology and Phthisiology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, University Teaching Hospital in Martin, Martin, Slovakia; Institute of Clinical Immunology and Medical Genetics, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, University Teaching Hospital in Martin, Martin, Slovakia
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