Effect of metabolic inhibitors on growth and brefeldin A formation in Curvularia lunata
Jazyk angličtina Země Spojené státy americké Médium print
Typ dokumentu časopisecké články
PubMed
564318
DOI
10.1007/bf02876588
Knihovny.cz E-zdroje
- MeSH
- antibakteriální látky biosyntéza MeSH
- antimetabolity farmakologie MeSH
- arsen farmakologie MeSH
- azidy farmakologie MeSH
- cyklopentany biosyntéza MeSH
- fluoridy farmakologie MeSH
- glukosa metabolismus MeSH
- jodacetamid farmakologie MeSH
- jodacetáty farmakologie MeSH
- mitosporické houby účinky léků růst a vývoj metabolismus MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- antibakteriální látky MeSH
- antimetabolity MeSH
- arsen MeSH
- azidy MeSH
- cyklopentany MeSH
- fluoridy MeSH
- glukosa MeSH
- jodacetamid MeSH
- jodacetáty MeSH
Arsenite as opposed to azide exerted a stronger inhibitory effect on brefeldin A production than on mycelial growth of cultures of Curvularia lunata. However, azide was a more potent inhibitor of mycelial growth than arsenite at 0.5 mM and 1.0 mM. The inhibitory effects of iodoacetate on growth and brefeldin A formation were significantly less potent than those of iosoacetamide. Increases in the levels of fluoride elicited a variable inhibitory effect on brefeldin A production and a corresponding decrease in biomass.
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Biochemical changes accompanying brefeldin A formation in Curvularia lunata
