In vitro production of the factors effective in the transfer of experimental autoimmune aspermatogenesis
Jazyk angličtina Země Česko Médium print
Typ dokumentu časopisecké články
PubMed
1100441
Knihovny.cz E-zdroje
- MeSH
- aktivace lymfocytů MeSH
- antigeny MeSH
- autoprotilátky analýza MeSH
- cytotoxické testy imunologické MeSH
- inhibice migrace buněk MeSH
- inhibiční faktory migrace makrofágů * MeSH
- makrofágy imunologie MeSH
- morčata MeSH
- spermatogeneze * MeSH
- spermie imunologie MeSH
- techniky in vitro MeSH
- testis imunologie MeSH
- tvorba protilátek MeSH
- zvířata MeSH
- Check Tag
- morčata MeSH
- mužské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- antigeny MeSH
- autoprotilátky MeSH
- inhibiční faktory migrace makrofágů * MeSH
We studied the biological effects of the factors released into the culture medium by the lymphocytes from animals sensitized with testicular antigen. The supernatants from cultures of these lymphocytes were active in vitro in the migration inhibition tests because they transferred the sensitivity to normal spleen cells. In vivo, they transferred aspermatogenesis in the allogeneic and xenogeneic system. The results suggest a specific effect on the behaviour of macrophages rather than a direct cytotoxic effect of the active factors.
