Effects of afterhyperpolarization on neuronal firing
Language English Country Ireland Media print
Document type Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.
PubMed
1391689
DOI
10.1016/0303-2647(92)90044-y
PII: 0303-2647(92)90044-Y
Knihovny.cz E-resources
- MeSH
- Mathematics MeSH
- Membrane Potentials physiology MeSH
- Models, Neurological * MeSH
- Neurons physiology MeSH
- Computer Simulation MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Research Support, U.S. Gov't, Non-P.H.S. MeSH
Stein's model for a neuron is studied. This model is modified to take into account the effects of afterhyperpolarization on the neuronal firing. The relative refractory phase, following the absolute one, is modelled by a time-increasing amplitude of postsynaptic potentials and it is also incorporated into the model. Besides the simulation of the model, some theoretical results and approximation methods are derived. Afterhyperpolarization tends to preserve the linearity of the frequency transfer characteristic and it has a limited effect on the moments of the interspike intervals in general. The main effects are seen at high firing rates and in the removal of short intervals in the interspike interval histogram.
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