Indirect transfer of resistance to imipenem in a strain of Pseudomonas aeruginosa
Journal of chemotherapy (Florence, Italy).
1991 Dec ;
3 (6) :
363-6.
Language English Country Great Britain, England Media print
Document type Journal Article
Persistent link
https://www.medvik.cz/link/pmid01819618
- MeSH
- Drug Resistance, Microbial genetics MeSH
- Cefazolin pharmacology MeSH
- Cefotaxime pharmacology MeSH
- Phenotype MeSH
- Imipenem pharmacology MeSH
- Conjugation, Genetic genetics MeSH
- Pseudomonas aeruginosa drug effects genetics physiology MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Cefazolin MeSH
- Cefotaxime MeSH
- Imipenem MeSH
Determinants of resistance of imipenem can be, in Pseudomonas aeruginosa strains resistant to this drug, transferred by transduction with wild-type phages as well as mobilized for conjugal transfer, as demonstrated by the indirect selection procedure. Exconjugants obtained in the latter type of experiments do not transfer imipenem resistance determinant to further recipient strains(s) by conjugation. Mobilized imipenem resistance is of non-hydrolytic character and its biochemical mechanism is unknown at present.
References provided by Crossref.org
Folia microbiologica.
2003 ;
48 (4) :
529-33.
