Elimination of plasmids pKM 101 and F'lac from Salmonella typhimurium and Escherichia coli by bisammonium salt. The effect of outer membrane pattern
Jazyk angličtina Země Spojené státy americké Médium print
Typ dokumentu časopisecké články
PubMed
1841858
DOI
10.1007/bf02814355
Knihovny.cz E-zdroje
- MeSH
- buněčná membrána účinky léků fyziologie MeSH
- Escherichia coli účinky léků genetika MeSH
- kvartérní amoniové sloučeniny farmakologie MeSH
- lipopolysacharidy farmakologie MeSH
- membránové lipidy fyziologie MeSH
- plazmidy účinky léků MeSH
- Salmonella typhimurium účinky léků genetika MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- kvartérní amoniové sloučeniny MeSH
- lipopolysacharidy MeSH
- membránové lipidy MeSH
- N,N'-bis(decyldimethyl)-1,6-hexanediammonium MeSH Prohlížeč
Plasmid-curing activity of N,N'-bis(decyldimethyl)-1,6-hexanediammonium dibromide, BDHD, was tested on six different plasmids in E. coli and plasmid pKM 101 in S. typhimurium. BDHD eliminated the F'lac plasmid from E. coli cells only with a low efficiency. Plasmid pKM 101 was eliminated from S. typhimurium cells significantly and this effect was dependent on an outer membrane pattern. A deep-rough mutant of S. typhimurium is completely resistant to curing activity of BDHD, while part-rough and smooth cells are susceptible to it. In contrast to pKM 101, a cryptic plasmid being present in S. typhimurium cells was not eliminated by BDHD. The curing activity of sodium dodecyl sulfate, acridine orange, crystal violet, and promethazine was also affected by the outer membrane pattern of S. typhimurium cells.
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