Decrease in the number of progenitors of erythrocytes (BFUe, CFUe), granulocytes and macrophages (GM-CFC) in bone marrow of rats after a 14-day flight onboard the Cosmos-2044 Biosatellite
Language English Country Czech Republic Media print
Document type Comparative Study, Journal Article
PubMed
2070886
Knihovny.cz E-resources
- MeSH
- Bone Marrow Cells * MeSH
- Erythroid Precursor Cells MeSH
- Granulocytes MeSH
- Hematopoietic Stem Cells * MeSH
- Hematopoiesis * MeSH
- Rats, Inbred Strains MeSH
- Space Flight * MeSH
- Rats MeSH
- Macrophages MeSH
- Cell Count MeSH
- Animals MeSH
- Check Tag
- Rats MeSH
- Male MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Comparative Study MeSH
A decrease in the number of progenitors of erythrocytes (BFUe, CFUe) and of granulocytes and macrophages (GM-CFC) in bone marrow was found in rats exposed to microgravitation during a 14-day flight onboard the Cosmos-2044 biosatellite when compared to control rats maintained under conditions of gravitation on the ground. The number of progenitors of both lineages of haemopoiesis was also decreased in synchronous control rats, thus suggesting that the pool of progenitors is influenced also by the action of the nonspecific space flight factors.
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