Does the synthesis of ribosomal RNA take place within nucleolar fibrillar centers or dense fibrillar components?
Language English Country Great Britain, England Media print
Document type Journal Article
PubMed
2539876
PII: 0248-4900(89)90013-0
Knihovny.cz E-resources
- MeSH
- Cell Nucleolus metabolism ultrastructure MeSH
- Cell Line MeSH
- DNA Topoisomerases, Type I metabolism MeSH
- Microscopy, Electron MeSH
- Pheochromocytoma MeSH
- HeLa Cells metabolism MeSH
- Immunohistochemistry MeSH
- Rats MeSH
- Humans MeSH
- Adrenal Gland Neoplasms MeSH
- RNA, Ribosomal biosynthesis MeSH
- RNA Polymerase I metabolism MeSH
- Animals MeSH
- Check Tag
- Rats MeSH
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- DNA Topoisomerases, Type I MeSH
- RNA, Ribosomal MeSH
- RNA Polymerase I MeSH
By means of immunocytochemistry performed on cryosections of cultured cells, RNA polymerase I was localized mainly to nucleolar fibrillar centers. The labelling of nucleolar dense fibrillar components was low and depended on the cell type. In contrast, DNA topoisomerase I and RNP complexes containing U3 snRNA were enriched in dense fibrillar components, their occurrence in fibrillar centers being usually much less.
Discontinuous transcription of ribosomal DNA in human cells
Visualization of the Nucleolus Using Ethynyl Uridine
Fluctuations of pol I and fibrillarin contents of the nucleoli
Reproduction of the FC/DFC units in nucleoli
Nucleolar DNA: the host and the guests
