Effect of granaticin on the activity of DNA-directed RNA polymerase from Streptomyces granaticolor
Language English Country United States Media print
Document type Journal Article
PubMed
2635132
DOI
10.1007/bf02814465
Knihovny.cz E-resources
- MeSH
- Anti-Bacterial Agents pharmacology MeSH
- DNA-Directed RNA Polymerases metabolism MeSH
- Naphthoquinones pharmacology MeSH
- Streptomyces drug effects enzymology MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Anti-Bacterial Agents MeSH
- DNA-Directed RNA Polymerases MeSH
- granaticin MeSH Browser
- Naphthoquinones MeSH
DNA-directed RNA polymerase was isolated from wild-type and mutant (asporogenic and granaticin overproducing) Streptomyces granaticolor. The effect of granaticin on the enzyme activity was compared with that of standard transcription inhibitors, rifampicin and rifamycin SV and shown to be zero.
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