Interaction of the effects of glucose and stress hormones on the activity of key enzymes of liver glycogen metabolism in rats
Language English Country Czech Republic Media print
Document type Journal Article
PubMed
2935890
Knihovny.cz E-resources
- MeSH
- Phosphorylase a metabolism MeSH
- Phosphorylases metabolism MeSH
- Stress, Physiological metabolism MeSH
- Glucose pharmacology MeSH
- Glycogen Synthase metabolism MeSH
- Immobilization MeSH
- Rats, Inbred Strains MeSH
- Liver Glycogen metabolism MeSH
- Corticosterone blood MeSH
- Rats MeSH
- Fasting MeSH
- Animals MeSH
- Check Tag
- Rats MeSH
- Male MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Phosphorylase a MeSH
- Phosphorylases MeSH
- Glucose MeSH
- Glycogen Synthase MeSH
- Liver Glycogen MeSH
- Corticosterone MeSH
Endogenous corticosterone released in protracted immobilization stress fails to increase the activity of liver glycogen synthase, perhaps because of the inhibition of synthase phosphatase by phosphorylase a. It was also found, that in rats subjected to acute immobilization stress the stimulation of the activity of both synthase a and total forms by glucose administered i.v. is depressed. Finally, in rats fasting for 24 h a paradoxical augmentation by glucose of the stimulatory effect of glycogenolytic hormones released in acute immobilization stress on phosphorylase a activity was observed.
