Expression of IL-2 receptors on peripheral blood lymphocytes from young adult and aged human donors
Jazyk angličtina Země Česko Médium print
Typ dokumentu časopisecké články
PubMed
3117600
Knihovny.cz E-zdroje
- MeSH
- aktivace lymfocytů MeSH
- dospělí MeSH
- fytohemaglutininy farmakologie MeSH
- interleukin-2 metabolismus MeSH
- lidé MeSH
- monoklonální protilátky MeSH
- receptory imunologické metabolismus MeSH
- receptory interleukinu-2 MeSH
- senioři MeSH
- stárnutí * MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- senioři MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- fytohemaglutininy MeSH
- interleukin-2 MeSH
- monoklonální protilátky MeSH
- receptory imunologické MeSH
- receptory interleukinu-2 MeSH
Peripheral blood mononuclear cells from young adult and aged human donors were activated with PHA and the expression of IL-2 receptors was examined. For the detection of IL-2 receptor-positive cells, flow cytofluorometry using monoclonal antibody Clonab IL-2R, fluorescein-conjugated swine anti-mouse IgG and fluorescence activated cell sorter FACS 440 were utilized. The age-related decrease in the expression of IL-2 receptors was observed: the percentage of IL-2 receptor-positive PBMC was substantially higher in the group of young adult donors than in the group of the aged individuals.
