Histochemistry of proteases in ependyma, choroid plexus and leptomeninges
Jazyk angličtina Země Německo Médium print
Typ dokumentu časopisecké články
PubMed
3284853
DOI
10.1007/bf00570337
Knihovny.cz E-zdroje
- MeSH
- ependym enzymologie MeSH
- histocytochemie MeSH
- inbrední kmeny potkanů MeSH
- krysa rodu Rattus MeSH
- meningy enzymologie MeSH
- mozek enzymologie MeSH
- neuropeptidy mozkomíšní mok MeSH
- plexus chorioideus enzymologie MeSH
- proteasy metabolismus MeSH
- zvířata MeSH
- Check Tag
- krysa rodu Rattus MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- neuropeptidy MeSH
- proteasy MeSH
Aminopeptidase M (APM), aminopeptidase A (APA), dipeptidyl peptidase IV (DPP IV) and gamma-glutamyl transferase (GGT) were demonstrated histochemically in cryostat sections of the rat brain to show the reaction pattern of ependyma, choroid plexus and leptomeninges. GGT was only demonstrable in the cell membranes of ependymal cells and in the leptomeninges; however, APA, APM and DAP IV showed a variable degree of activity in the capillary endothelium of the choroid plexus as well as in the leptomeninges. On the basis of these results, it is postulated that peptides in the cerebrospinal fluid can be cleaved extraventricularly by the enzymes demonstrated in the leptomeninges.
