Changes in the migratory activity of polymorphonuclear leukocytes after administration of Freund's adjuvant
Jazyk angličtina Země Spojené státy americké Médium print
Typ dokumentu časopisecké články
PubMed
3924799
DOI
10.1007/bf02923514
Knihovny.cz E-zdroje
- MeSH
- adjuvancia imunologická imunologie MeSH
- chemotaktické faktory biosyntéza MeSH
- chemotaxe leukocytů * MeSH
- endotoxiny imunologie MeSH
- Escherichia coli imunologie MeSH
- králíci MeSH
- Listeria monocytogenes imunologie MeSH
- neutrofily imunologie MeSH
- zvířata MeSH
- Check Tag
- králíci MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- adjuvancia imunologická MeSH
- chemotaktické faktory MeSH
- endotoxiny MeSH
Spontaneous and chemotactic activity of polymorphonuclear leukocytes, obtained from the peritoneal cavity, was studied after administration of complete and incomplete Freund's adjuvant to rabbits at intervals of 18-26 d after adjuvant injection. Whereas injection of both complete and incomplete adjuvant increased spontaneous migration of rabbit polymorphonuclear leukocytes, the migration directed by the chemotactic signal, induced in fresh serum by E. coli endotoxin, was decreased. The chemotaxigenic activity of two factors, isolated from cell walls of Listeria monocytogenes was also tested: factor Ei (its most potent component is lipopolysaccharide) and a purified phenol extract of lipopeptidopolysaccharide nature.
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