Catabolite repression of different inducible enzymes in Escherichia coli and the effect of cAMP
Language English Country United States Media print
Document type Journal Article
PubMed
6269972
DOI
10.1007/bf02927249
Knihovny.cz E-resources
- MeSH
- Cyclic AMP pharmacology MeSH
- beta-Galactosidase metabolism MeSH
- Enzyme Induction MeSH
- Enzyme Repression drug effects MeSH
- Escherichia coli drug effects enzymology metabolism MeSH
- Gluconates metabolism MeSH
- Glucose metabolism MeSH
- Glycerol metabolism MeSH
- L-Serine Dehydratase metabolism MeSH
- Malate Dehydrogenase metabolism MeSH
- Tryptophanase metabolism MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Cyclic AMP MeSH
- beta-Galactosidase MeSH
- gluconic acid MeSH Browser
- Gluconates MeSH
- Glucose MeSH
- Glycerol MeSH
- L-Serine Dehydratase MeSH
- Malate Dehydrogenase MeSH
- Tryptophanase MeSH
Simultaneous induction of two enzymes sensitive to catabolite repression does not lead to an additive decrease of the specific activity of the two. Exogenously added cAMP increases the specific activity of catabolically repressed enzymes, irrespective of whether the enzyme is induced separately or simultaneously with another enzyme. In the presence of 12 different substrates metabolized by inducible enzymes glucose does not bring about catabolite repression. Synthesis of cAMP is identical with that occurring under conditions when glucose brings about catabolite repression.
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Proc Natl Acad Sci U S A. 1971 Sep;68(9):2258-62 PubMed
Nat New Biol. 1971 Jun 2;231(22):139-42 PubMed
Proc Natl Acad Sci U S A. 1974 Jun;71(6):2324-8 PubMed
J Bacteriol. 1970 Aug;103(2):513-6 PubMed
Proc Natl Acad Sci U S A. 1976 Oct;73(10):3476-9 PubMed
Folia Microbiol (Praha). 1981;26(1):1-7 PubMed
