Failure to confirm the role of immunological tolerance to B (MHC) alloantigens in the growth of RSV-induced tumours in chickens
Language English Country Czech Republic Media print
Document type Journal Article
PubMed
6292007
Knihovny.cz E-resources
- MeSH
- Immune Tolerance * MeSH
- Isoantigens immunology MeSH
- Chickens MeSH
- Sarcoma, Avian immunology MeSH
- Avian Sarcoma Viruses immunology MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Isoantigens MeSH
Chickens of the inbred "regressor" line CB (B12/B12) were made tolerant to the B13 (MHC) alloantigen of the congenic "progressor" line CC and then challenged with Prague strain of Rous sarcoma virus of subgroup C. No changes in tumour growth between tolerant and control groups were observed. These results suggest that there is no cross-reactivity between B13 alloantigen and RSV-induced tumour antigens.
src-specific immunity in inbred chickens bearing v-src DNA- and RSV-induced tumors