The appearance of an IgD-like molecule on pig lymphocytes during ontogeny
Language English Country United States Media print
Document type Journal Article
PubMed
6667918
DOI
10.1007/bf02879687
Knihovny.cz E-resources
- MeSH
- Immunoglobulin D analysis MeSH
- Immunoglobulin M analysis MeSH
- Lymphocytes immunology MeSH
- Swine, Miniature embryology immunology MeSH
- Animals, Newborn immunology MeSH
- Fetus immunology MeSH
- Swine MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Immunoglobulin D MeSH
- Immunoglobulin M MeSH
An IgD-like molecule was found on the surface of pig fetal lymphocytes using guinea pig anti-human IgD antisera and indirect immunofluorescence. The binding of antiIgD antisera could be specifically inhibited with human IgD. Surface IgD-like molecules were found later in ontogeny than surface IgM (after about 70 d of gestation in the spleen). There is evidence for their endogenous origin. The number of lymphocytes bearing IgD-like molecules rapidly increased during ontogeny.
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