Relationship between the structure of carbonylcyanide phenylhydrazones and inhibition of growth of microorganisms, stimulation of respiration of yeast cells and rat liver mitochondria
Jazyk angličtina Země Spojené státy americké Médium print
Typ dokumentu časopisecké články
PubMed
411721
DOI
10.1007/bf02877675
Knihovny.cz E-zdroje
- MeSH
- Bacillus cereus růst a vývoj MeSH
- houby růst a vývoj MeSH
- jaterní mitochondrie metabolismus MeSH
- karbonylkyanid-m-chlorfenylhydrazon analogy a deriváty farmakologie MeSH
- karbonylkyanid-p-trifluormethoxyfenylhydrazon farmakologie MeSH
- krysa rodu Rattus MeSH
- nitrily farmakologie MeSH
- Saccharomyces cerevisiae růst a vývoj metabolismus MeSH
- spotřeba kyslíku MeSH
- vztahy mezi strukturou a aktivitou MeSH
- zvířata MeSH
- Check Tag
- krysa rodu Rattus MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- karbonylkyanid-m-chlorfenylhydrazon MeSH
- karbonylkyanid-p-trifluormethoxyfenylhydrazon MeSH
- nitrily MeSH
The effect of ten derivatives of carbonylcyanide phenylhydrazone on growth of bacteria, yeast and different species of filamentous fungi was investigated. In yeast and mitochondria isolated from rat liver the effect of these derivatives on the respiratory activity was also followed. The relative efficiency of the individual derivatives of carbonylcyanide phenylhydrazone was determined on the basis of the results obtained. It was shown that derivatives, in which the substituent on the benzene ring causes simultaneously an increase of acidity and lipophilicity of the derivative as compared with the non-substituted carbonylcyanide phenylhydrazone (4-trifluoromethoxy-, 3-chloro-, 4-chloro and 3,4-dichloro-derivatives) were most effective.
Zobrazit více v PubMed
J Membr Biol. 1975-1976;25(3-4):361-80 PubMed
Folia Microbiol (Praha). 1974;19(5):367-72 PubMed
J Supramol Struct. 1975;3(3):201-13 PubMed
Biochem Biophys Res Commun. 1962 May 4;7:272-5 PubMed
Biochem J. 1965 Dec;97(3):658-62 PubMed
Biochem J. 1967 Aug;104(2):588-600 PubMed
Biochemistry. 1963 Mar-Apr;2:357-61 PubMed
Biochem J. 1958 Jun;69(2):306-11 PubMed
Proc Natl Acad Sci U S A. 1976 Sep;73(9):3141-5 PubMed
J Biol Chem. 1956 Nov;223(1):147-56 PubMed
Proc Natl Acad Sci U S A. 1974 Feb;71(2):288-92 PubMed
Biochem Soc Trans. 1976;4(3):399-430 PubMed
J Biol Chem. 1975 Jan 25;250(2):396-408 PubMed
Biochim Biophys Acta. 1962 Sep 10;63:46-54 PubMed
J Biol Chem. 1956 Aug;221(2):609-18 PubMed
Biochem Pharmacol. 1964 Mar;13:285-318 PubMed
Proc Natl Acad Sci U S A. 1968 Feb;59(2):484-90 PubMed
Folia Microbiol (Praha). 1967;12(1):56-63 PubMed
Biochim Biophys Acta. 1975 Aug 11;396(2):165-74 PubMed
Biochem Biophys Res Commun. 1967 Oct 26;29(2):153-7 PubMed
J Biol Chem. 1948 Apr;173(2):807 PubMed
Anal Biochem. 1961 Aug;2:335-43 PubMed
Biochemistry. 1963 Sep-Oct;2:1142-7 PubMed
Bacteriol Rev. 1972 Jun;36(2):172-230 PubMed
Biochim Biophys Acta. 1976 Sep 27;456(2):129-48 PubMed
Effect of inhibitors on acid production by baker's yeast
