Collagen metabolism in patients with myocardial infarction
Language English Country Czech Republic Media print
Document type Journal Article
PubMed
7172687
Knihovny.cz E-resources
- MeSH
- Time Factors MeSH
- Adult MeSH
- Hydroxylysine blood MeSH
- Hydroxyproline blood MeSH
- Myocardial Infarction metabolism MeSH
- Collagen metabolism MeSH
- Blood Proteins MeSH
- Middle Aged MeSH
- Humans MeSH
- Proteins * MeSH
- Aged MeSH
- Carrier Proteins * MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Aged MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- c1q-binding proteins MeSH Browser
- Hydroxylysine MeSH
- Hydroxyproline MeSH
- Collagen MeSH
- Blood Proteins MeSH
- Proteins * MeSH
- Carrier Proteins * MeSH
The healing of myocardial infarction is accompanied by an increased accumulation of collagen in the heart muscle. Indexes of collagen metabolism (serum hydroxyproline, hydroxylysine and collagen-like protein concentration) were measured in 60 patients with myocardial infarction and 30 healthy blood donors. Determinations were carried out 1, 2, 3 days after admission and between the 10th-14th and 21st-25th day of the illness. It was found that hydroxyproline and hydroxylysine decreased in the first days of the disease, and subsequently increased in the course of the healing process accompanied by an increased collagen-like protein level. The changes did not depend on the total protein concentration.
