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A new approach to in vitro studies of antigenic response in earthworms

. 1994 Sep-Oct ; 18 (5) : 363-7.

Language English Country United States Media print

Document type Journal Article, Research Support, Non-U.S. Gov't

A method for in vitro cultivation of earthworm gut wall tissue explants is described. Tissue explants are able to respond to protein antigen by secretion of antigen-binding protein into the culture medium. Large irregular cells and round-shaped cells are released from tissue explants during the cultivation. This method represents an advantageous tool for in vitro studies providing the possibility of parallel assays from the same donor.

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