Age-dependent changes of baroreflex efficiency in Dahl rats: effects of high salt intake
Jazyk angličtina Země Česko Médium print
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
8218156
Knihovny.cz E-zdroje
- MeSH
- baroreflex účinky léků fyziologie MeSH
- fenylefrin farmakologie MeSH
- genotyp MeSH
- inbrední kmeny potkanů MeSH
- krevní tlak fyziologie MeSH
- krysa rodu Rattus MeSH
- sodík dietní farmakologie MeSH
- srdeční frekvence fyziologie MeSH
- stárnutí fyziologie MeSH
- zvířata MeSH
- Check Tag
- krysa rodu Rattus MeSH
- mužské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Názvy látek
- fenylefrin MeSH
- sodík dietní MeSH
The age-dependent changes in baroreflex control of heart rate were studied in inbred Dahl rats. At the age of 8 weeks the baroreflex slope was significantly greater in salt-resistant (R/Jr) than in salt-sensitive (S/Jr) rats fed a low-salt diet. The reverse was true in 16-week-old animals. High salt intake (8% NaCl diet for 4 weeks) suppressed baroreflex efficiency in both age groups of S/Jr animals whereas no effects occurred in R/Jr rats. Baroreflex slope was, however, significantly lower in young S/Jr rats with a severe form of salt hypertension than in adult salt-loaded S/Jr rats in which only a moderate blood pressure elevation was observed.
Altered Balance between Vasoconstrictor and Vasodilator Systems in Experimental Hypertension
