The fate of protein antigen in earthworms: study in vivo
Jazyk angličtina Země Nizozemsko Médium print
Typ dokumentu časopisecké články
PubMed
8349310
DOI
10.1016/0165-2478(93)90044-3
PII: 0165-2478(93)90044-3
Knihovny.cz E-zdroje
- MeSH
- antigeny imunologie metabolismus MeSH
- endopeptidasy metabolismus MeSH
- injekce MeSH
- kyselina arsanilová aplikace a dávkování MeSH
- Oligochaeta imunologie MeSH
- proteiny červů imunologie MeSH
- sérový albumin aplikace a dávkování imunologie farmakokinetika MeSH
- tělesné tekutiny metabolismus MeSH
- zvířata MeSH
- Check Tag
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- antigeny MeSH
- endopeptidasy MeSH
- kyselina arsanilová MeSH
- proteiny červů MeSH
- sérový albumin MeSH
Parenteral administration of antigen induces in the earthworms Lumbricus terrestris and Eisenia foetida the formation of antigen-binding protein. Labelled antigen was efficiently digested in the coelomic fluids of both species since the total amount of radioactivity in the coelomic fluids decreased. Antigen internalized in the free coelomocytes of both species was present in a TCA-precipitable form, although the decline of total radioactivity was higher than in the coelomic fluid, indicating that the TCA-nonprecipitable fragments are rapidly released from coelomocytes into the coelomic fluid. Within the first 24 h after administration, labelled antigen was detected throughout all tissues except for the epidermis and cuticle, and after 4 days it was found in the chloragogenic tissue around the gut, dorsal vein and typhlosole.
Citace poskytuje Crossref.org
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