První ceský hyperimunní imunoglobulin proti cytomegaloviru
[The first hyperimmune immunoglobulin against cytomegaloviruses made in the Czech Republic]
Language Czech Country Czech Republic Media print
Document type English Abstract, Journal Article
PubMed
8402824
- MeSH
- Cytomegalovirus Infections diagnosis therapy MeSH
- Cytomegalovirus immunology MeSH
- Adult MeSH
- Pregnancy Complications, Infectious prevention & control therapy MeSH
- Immunoglobulins, Intravenous therapeutic use MeSH
- Infant MeSH
- Humans MeSH
- Antibodies, Viral analysis MeSH
- Pregnancy MeSH
- Check Tag
- Adult MeSH
- Infant MeSH
- Humans MeSH
- Male MeSH
- Pregnancy MeSH
- Female MeSH
- Publication type
- English Abstract MeSH
- Journal Article MeSH
- Names of Substances
- Immunoglobulins, Intravenous MeSH
- Antibodies, Viral MeSH
The Czech immunoglobulin CMV was administered to 16 subjects with active CMV infection--mostly women with repeated miscarriages, CMV primoinfection during pregnancy, to children with congenital CMV infection and to patients with other clinical forms. The immunoglobulin was administered in a single dose or repeatedly by the intramuscular route. The decline of activity of the CMV infection was demonstrated by a decline of specific IgM CMV antibodies, disappearance of previously assessed viriuria and isolation of CMV in smears from the uterine cervix.
