The fate of protein antigen in earthworms: study in vitro
Jazyk angličtina Země Nizozemsko Médium print
Typ dokumentu časopisecké články
PubMed
8458632
DOI
10.1016/0165-2478(93)90139-s
PII: 0165-2478(93)90139-S
Knihovny.cz E-zdroje
- MeSH
- antigeny metabolismus MeSH
- Oligochaeta imunologie metabolismus MeSH
- proteasy metabolismus MeSH
- proteiny imunologie metabolismus MeSH
- trávicí systém cytologie imunologie metabolismus MeSH
- zvířata MeSH
- Check Tag
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- antigeny MeSH
- proteasy MeSH
- proteiny MeSH
Earthworm coelomocytes digest protein antigen in vitro. Proteolytic activity was detected both in cell-free coelomic fluid and in cell cultures of free coelomocytes which are effectors of earthworm immunodefense mechanisms. Antigen is cleaved either intracellularly or by proteolytic enzymes released by coelomocytes into the medium. Proteolysis was observed both in non-stimulated and antigen-stimulated cultures. Since significantly higher proteolysis was shown in supernatants from cultures of antigen-stimulated coelomocytes, we can assume that the release of proteolytic enzymes was inducible.
Citace poskytuje Crossref.org
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