The effect of chloroform-extractable secondary metabolites of filamentous fungi on the movement of respiratory tract cilia of one-day-old chicks in vitro
Jazyk angličtina Země Spojené státy americké Médium print
Typ dokumentu časopisecké články
PubMed
8851467
DOI
10.1007/bf02816536
Knihovny.cz E-zdroje
- MeSH
- chloroform MeSH
- cilie účinky léků fyziologie MeSH
- dýchací soustava účinky léků patofyziologie MeSH
- houby metabolismus patogenita MeSH
- kur domácí MeSH
- lidé MeSH
- mykotoxiny izolace a purifikace toxicita MeSH
- novorozená zvířata MeSH
- syndrom nezdravých budov etiologie MeSH
- techniky in vitro MeSH
- trachea účinky léků patofyziologie MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- chloroform MeSH
- mykotoxiny MeSH
The ciliostatic activity of the chloroform-extractable metabolites of 72 strains of filamentous fungi growing in a liquid medium, on tracheal cilia from 1-d-old chicks in vitro was evaluated. Forty-eight of the investigated strains produced ciliostatic metabolites; 13, 11, 16, and 25% of the strains stopped the movement of cilia after 1, 2, 3, 6 d, respectively. The results are discussed in relationship with chronic bronchitis of people working with mouldy materials, living in mouldy dwellings and with the "sick-building syndrome".
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