Adenohypophyseal ascorbic acid: influences of oestradiol and methylene blue
Language English Country Czech Republic Media print
Document type Journal Article
PubMed
8869269
Knihovny.cz E-resources
- MeSH
- Pituitary Gland, Anterior metabolism MeSH
- Estradiol pharmacology MeSH
- Rats MeSH
- Ascorbic Acid antagonists & inhibitors blood metabolism MeSH
- Methylene Blue pharmacology MeSH
- Osmolar Concentration MeSH
- Rats, Wistar MeSH
- Animals MeSH
- Check Tag
- Rats MeSH
- Male MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Estradiol MeSH
- Ascorbic Acid MeSH
- Methylene Blue MeSH
The ascorbic acid (AA) concentration in anterior pituitary and blood plasma was measured by the Roe-Kuether method in control rats and rats treated with oestradiol benzoate alone, methylene blue alone and with both oestradiol and methylene blue. We have found that methylene blue alone caused a significant drop in hypophyseal both AA and plasma AA concentrations. Methylene blue treatment prevented the increase in plasma AA concentration in oestradiol benzoate-treated rats.
