In 200 children residing permanently in a region with a high level of atmospheric pollution, indicators of humoral immunity, salivary immunity and specific IgE antibodies were determined before and after 14 days' attendance at an "outdoor school" in rural areas with a very low level of atmospheric pollution. A marked reduction of elevated albumine levels, which are characteristic of irritation or even inflammation in the oral cavity or respiratory tract, was found, as well as increasing levels of Slg A and lysozyme in saliva. The two-week stay in the outdoor school resulted in decreased IgE specific antibodies of the respiratory type of allergy (CAP Phadiatop). In the group of atopic children there were found high total IgE levels, with a trend of depression after 2 weeks in the outdoor school. Higher values of some immunoglobulins were observed, while low levels of IgA were found in some children with high frequency of respiratory diseases. The irritant effect of polluted atmosphere and the quality of indoor atmosphere influence some immunological parameters in children.

Public Health Institute Immunological Department Usti nad Labem Czech Republic

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