Dietary silymarin improves removal of low density lipoproteins by the perfused rat liver
Acta Universitatis Palackianae Olomucensis Facultatis Medicae.
1998 ;
141 () :
39-40.
Language English Country Czech Republic Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
Persistent link
https://www.medvik.cz/link/pmid09684480
PubMed
9684480
Knihovny.cz E-resources
- MeSH
- Anticholesteremic Agents administration & dosage pharmacology MeSH
- Cholesterol, Dietary administration & dosage MeSH
- Liver metabolism MeSH
- Rats MeSH
- Lipoproteins, LDL metabolism MeSH
- Rats, Wistar MeSH
- Silymarin administration & dosage pharmacology MeSH
- Animals MeSH
- Check Tag
- Rats MeSH
- Female MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Anticholesteremic Agents MeSH
- Cholesterol, Dietary MeSH
- Lipoproteins, LDL MeSH
- Silymarin MeSH
Silymarin administered to the rats concurrently with high cholesterol diet normalized the high cholesterol diet-induced retardation of disappearance of low density lipoproteins (LDL) from the medium during recirculating perfusion of livers from these rats. We suggest that the improvement of LDL removal by the liver after silymarin treatment contributes to the antihypercholesterolemic effect of silymarin.
