Methamphetamine--properties and analytical methods of enantiomer determination
Language English Country Ireland Media print
Document type Journal Article, Research Support, Non-U.S. Gov't, Review
PubMed
9800366
DOI
10.1016/s0379-0738(98)00104-2
PII: S0379-0738(98)00104-2
Knihovny.cz E-resources
- MeSH
- Electrophoresis, Capillary MeSH
- Immunoassay MeSH
- Humans MeSH
- Methamphetamine analysis chemistry metabolism toxicity MeSH
- Stereoisomerism MeSH
- Chromatography, High Pressure Liquid MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
- Names of Substances
- Methamphetamine MeSH
Methamphetamine is one of the most frequently abused drugs of today. Due to its stereogenic center, it can exist as single enantiomer. Like many other chiral compounds, methamamphetamine enantiomers exhibit different pharmacological effects on living organisms. For this reason, it is necessary to develop enantioselective and sufficiently sensitive methods of determination. This review focuses on methamphetamine with an accent on analytical chemistry and especially on chiral separations of this toxicologically important compound.
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