The asymmetric distribution of interphasic silver-stained nucleolus organizer regions in human and rat proerythroblasts
Jazyk angličtina Země Česko Médium print
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
10732720
Knihovny.cz E-zdroje
- MeSH
- barvení stříbrem MeSH
- buněčné jadérko ultrastruktura MeSH
- druhová specificita MeSH
- erytroidní prekurzorové buňky ultrastruktura MeSH
- erytropoéza MeSH
- kostní dřeň ultrastruktura MeSH
- krysa rodu Rattus MeSH
- lidé MeSH
- organizátor jadérka ultrastruktura MeSH
- zvířata MeSH
- Check Tag
- krysa rodu Rattus MeSH
- lidé MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
The distribution of SSPs representing AgNORs was studied in human as well as rat proerythroblasts to provide information on the distribution of these nucleolar components in highly immature and proliferating non-neoplastic cells. The distribution of SSPs was asymmetric and most of the cells contained one nucleolus which possessed a larger number of these nucleolar components than the remaining nucleoli. Such nucleolus might be functionally dominant, since the number of nucleolar SSPs is apparently related to the nucleolar biosynthetic activity. On the other hand, when a proerythroblast possessed only one nucleolus, the number of SSPs in such a cell was very similar to the sum of SSPs in a polynucleolar cell. The asymmetric distribution of SSPs characteristic for most proerythroblasts disappeared in the terminal stages of the erythroblastic development. Cells in such stages, as described previously, were characterized by the presence of a limited number of single SSPs.
Asymmetrical distribution of the transcriptionally competent NORs in mitosis
