Characterization of Amphioxus AmphiVent, an evolutionarily conserved marker for chordate ventral mesoderm
Language English Country United States Media print
Document type Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.
PubMed
11309850
DOI
10.1002/gene.1021
PII: 10.1002/gene.1021
Knihovny.cz E-resources
- MeSH
- Neural Crest metabolism MeSH
- DNA-Binding Proteins genetics MeSH
- Gene Duplication MeSH
- Embryo, Nonmammalian metabolism ultrastructure MeSH
- Gene Expression MeSH
- Phylogeny MeSH
- Genes, Homeobox MeSH
- Homeodomain Proteins chemistry classification genetics physiology MeSH
- In Situ Hybridization MeSH
- Mesoderm metabolism MeSH
- Evolution, Molecular MeSH
- Molecular Sequence Data MeSH
- Chordata, Nonvertebrate embryology genetics ultrastructure MeSH
- Amino Acid Sequence MeSH
- Base Sequence MeSH
- Threonine chemistry MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Research Support, U.S. Gov't, Non-P.H.S. MeSH
- Names of Substances
- DNA-Binding Proteins MeSH
- Homeodomain Proteins MeSH
- Threonine MeSH
- Vent protein, Amphioxus MeSH Browser
Structure and developmental expression are described for amphioxus AmphiVent, a homolog of vertebrate Vent genes. In amphioxus, AmphiVent-expressing ventral mesoderm arises at midneurula by outgrowth from the paraxial mesoderm, but in vertebrates, Vent-expressing ventral mesoderm originates earlier, at the gastrula stage. In other embryonic tissues (nascent paraxial mesoderm, neural plate, endoderm, and tailbud), AmphiVent and its vertebrate homologs are expressed in similar spatiotemporal domains, indicating conservation of many Vent gene functions during chordate evolution. The ventral mesoderm evidently develops precociously in vertebrates because their relatively large embryos probably require an early and extensive deployment of the mesoderm-derived circulatory system. The vertebrate ventral mesoderm, in spite of its strikingly early advent, still resembles the nascent ventral mesoderm of amphioxus in expressing Vent homologs. This coincidence may indicate that Vent homologs in vertebrates and amphioxus play comparable roles in ventral mesoderm specification.
References provided by Crossref.org
Wnt/β-catenin signaling is an evolutionarily conserved determinant of chordate dorsal organizer
A conserved regulatory program initiates lateral plate mesoderm emergence across chordates
GENBANK
AF255044, AF255045, AJ131094, AJ131095, Q22909, X92851, X98849, Y08821, Y08822
RefSeq
NM_006562, NM_010691, NM_010692
