Theory of the age dependence of mortality from congenital defects
Jazyk angličtina Země Irsko Médium print
Typ dokumentu časopisecké články
PubMed
11557286
DOI
10.1016/s0047-6374(01)00325-6
PII: S0047-6374(01)00325-6
Knihovny.cz E-zdroje
- MeSH
- biologické modely * MeSH
- dítě MeSH
- infekční nemoci mortalita MeSH
- lidé MeSH
- stárnutí fyziologie MeSH
- vrozené vady mortalita MeSH
- Check Tag
- dítě MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
A theory is presented, based on the evidence that the congenital defect of an individual is at one of many different levels. It is supposed that the individual mortality risk from congenital defect is lognormally or normally distributed in the population. The relationship between childhood mortality from seven congenital defects and age is described. It uses data from the US during the period 1979-1991. Mortality from five congenital defects is inversely proportional to age. Mortality from two congenital defects is inversely proportional to the second power of age. The presented theory explains these two observed types of mortality decline with age. Childhood mortality from some infectious diseases is also inversely proportional to age during childhood in different populations. It follows from this theory that the death from these infectious diseases up the age of 10 years may be caused by a hidden congenital frailty.
Citace poskytuje Crossref.org
Database of age trajectories of mortality in 110 countries and web application: Data report
Decrease of total activity with time at long distances from a nuclear accident or explosion