Inactivation of individual cells by divers ions at different LET values
Language English Country Italy Media print
Document type Comparative Study, Journal Article, Research Support, Non-U.S. Gov't
PubMed
11771548
Knihovny.cz E-resources
- MeSH
- Models, Biological * MeSH
- Cell Nucleus radiation effects MeSH
- Cells radiation effects MeSH
- Ions * MeSH
- Skin cytology radiation effects MeSH
- Humans MeSH
- Linear Energy Transfer * MeSH
- Mice MeSH
- Protons MeSH
- Carbon * MeSH
- Cell Survival radiation effects MeSH
- Dose-Response Relationship, Radiation MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Mice MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Comparative Study MeSH
- Names of Substances
- Ions * MeSH
- Protons MeSH
- Carbon * MeSH
A new formula linking the shape of survival curve to the inactivation probabilities after different numbers of cell hits has been derived. It has been used in analyzing recent experimental data obtained with monolayer cells irradiated at definite values of LET (in different parts of Bragg peaks). The new approach allows not only deriving the values of inactivation probabilities at given LET values; unexpected consequences seem to follow especially for inactivation characteristics of carbon ions in different parts of the Bragg peak, too.
