Identification of the cockroach neuropeptide Pea-CAH-II as a second adipokinetic hormone in the firebug Pyrrhocoris apterus
Language English Country United States Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
11836011
DOI
10.1016/s0196-9781(01)00627-1
PII: S0196978101006271
Knihovny.cz E-resources
- MeSH
- Heteroptera chemistry MeSH
- Insect Hormones isolation & purification MeSH
- Pyrrolidonecarboxylic Acid analogs & derivatives MeSH
- Neuropeptides isolation & purification MeSH
- Cockroaches chemistry MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- adipokinetic hormone, beetle MeSH Browser
- Insect Hormones MeSH
- Pyrrolidonecarboxylic Acid MeSH
- Led-CC-II peptide MeSH Browser
- Neuropeptides MeSH
- Pea-CAH-II neuropeptide MeSH Browser
A new member of the AKH/RPCH family was isolated from the corpora cardiaca of the firebug Pyrrhocoris apterus. It is the second adipokinetic peptide identified in this species. The peptide was characterized and its structure was deduced from the multiple MS(N) electrospray mass spectra as that of an octapeptide with the sequence pGlu-Leu-Thr-Phe-Thr-Pro-Asn-Trp-NH(2.) The peptide differs from the original P. apterus AKH (Pya-AKH) by one amino acid in position 3. Topical application and/or injection of the peptide induced lipid mobilization, but was inactive in mobilization of carbohydrates.
Institute of Entomology Academy of Sciences Branisovská 31 CZ 370 05 Ceské Budejovice Czech Republic
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