The histopathological characterization of oral Candida leukoplakias
Language English Country United States Media print
Document type Journal Article
PubMed
11899480
DOI
10.1007/bf02814437
Knihovny.cz E-resources
- MeSH
- Atrophy pathology MeSH
- Staining and Labeling MeSH
- Biopsy MeSH
- Candida isolation & purification MeSH
- Hyphae isolation & purification MeSH
- Muscle, Skeletal pathology MeSH
- Periodic Acid MeSH
- Middle Aged MeSH
- Humans MeSH
- Candidiasis, Oral microbiology pathology MeSH
- Leukoplakia, Oral microbiology pathology MeSH
- Aged MeSH
- Mouth Mucosa microbiology pathology MeSH
- Inflammation pathology MeSH
- Check Tag
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Aged MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Periodic Acid MeSH
Sixty four biopsy specimens of oral Candida leukoplakias were examined. Histological sections were stained with periodic acid-Schiff (PAS) reagent and by Grocott's silver method. C. albicans isolates were cultivated from all the patients but fungal hyphae were proved histologically only in 23 of them. PAS-positive and Grocott-positive elements were exclusively observed in the superficial epithelial layers, e.g., the cornified layer and the stratum granulosum. The inflammatory reaction was characterized by an early phase during which polymorphonuclear cells predominated. The skeletal muscle fascicles immediately adjacent to the infected epithelium showed striking degeneration and atrophy associated with a marked infiltrate of chronic inflammatory cells.
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