A miniature fiber optic surface plasmon resonance sensor for fast detection of Staphylococcal enterotoxin B
Language English Country England, Great Britain Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
11959482
DOI
10.1016/s0956-5663(02)00013-1
PII: S0956566302000131
Knihovny.cz E-resources
- MeSH
- Time Factors MeSH
- Equipment Design MeSH
- Enterotoxins analysis MeSH
- Immunoassay instrumentation methods MeSH
- Miniaturization MeSH
- Optical Fibers MeSH
- Surface Plasmon Resonance instrumentation methods MeSH
- Sensitivity and Specificity MeSH
- Fiber Optic Technology instrumentation methods MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- enterotoxin B, staphylococcal MeSH Browser
- Enterotoxins MeSH
A fiber optic surface plasmon resonance (SPR) biosensor for detection of Staphylococcal enterotoxin B (SEB) is reported. The sensor is based on spectral interrogation of surface plasmons in a miniature sensing element based on a side-polished single-mode optical fiber with a thin metal overlayer. For specific detection of SEB, the SPR sensor is functionalized with a covalently crosslinked double-layer of antibodies against SEB. The SPR biosensor is demonstrated to be able to detect ng/ml concentrations of SEB in less than 10 min.
References provided by Crossref.org
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