Detection of anti-Candida antibodies in neonates from a Neonatal Intensive Care Unit
Language English Country United States Media print
Document type Journal Article
PubMed
12094742
DOI
10.1007/bf02817656
Knihovny.cz E-resources
- MeSH
- Candida albicans growth & development immunology isolation & purification MeSH
- Intensive Care Units, Neonatal statistics & numerical data MeSH
- Candidiasis blood diagnosis immunology MeSH
- Humans MeSH
- Infant, Premature, Diseases epidemiology MeSH
- Infant, Newborn MeSH
- Prevalence MeSH
- Antibodies, Fungal blood MeSH
- Check Tag
- Humans MeSH
- Infant, Newborn MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Antibodies, Fungal MeSH
Anti-Candida antibodies were determined in a group of preterm neonates from a neonatal intensive care unit with serious diseases including candidemia. Antibodies to C. albicans blastospores, i.e. antibodies to C. albicans surface mannan and to C. albicans germ tubes were detected. Higher titers of antibodies to blastospores (1:320) occurred in all patients examined while antibodies to C. albicans germ tubes (with the highest titer of 1:160) were present in 32 out of 66 neonates examined. The highest titers of both anti-C. albicans blastospore antibodies and anti-C. albicans germ tube antibodies were detected in neonates with candidemia and disorders of saccharide metabolism.
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