Detection of anti-Candida antibodies by the indirect immunofluorescence assay in patients with cancer in the orofacial region
Jazyk angličtina Země Spojené státy americké Médium print
Typ dokumentu časopisecké články
PubMed
12630328
DOI
10.1007/bf02818680
Knihovny.cz E-zdroje
- MeSH
- Candida albicans imunologie izolace a purifikace MeSH
- fluorescenční protilátková technika nepřímá MeSH
- kandidóza komplikace imunologie mikrobiologie MeSH
- karcinom krev komplikace mikrobiologie MeSH
- lidé MeSH
- nádory úst krev komplikace mikrobiologie MeSH
- orální kandidóza komplikace imunologie mikrobiologie MeSH
- protilátky fungální krev MeSH
- ústní sliznice mikrobiologie MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- protilátky fungální MeSH
An indirect immunofluorescence assay was performed to detect antibodies to Candida albicans blastospores and germ tubes. Serum specimens were obtained from 82 patients with neoplastic diseases in the orofacial region and thrush of the oral mucosa. C. albicans was identified in the oral cavity of 63 patients investigated but serum anti-Candida antibodies were detected in only 23 of them. Serological examination showed that titers of antibodies to C. albicans blastospores ranged from 1:20 to 1:1280. High titers from 1:640 to 1:1280 were detected in patients without antibiotic, cytostatic, or radiotherapeutic treatment. The titers of antibodies to C. albicans germ tubes ranged from 1:20 to 1:640. Our results indicate that titers of antibodies to the C. albicans germ tubes were lower and were detected in a smaller number of patients.
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