Postnatal lower jaw dentition in different phenotypes of tabby mice
Language English Country Great Britain, England Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
- MeSH
- Tooth Abnormalities genetics pathology physiopathology MeSH
- X Chromosome MeSH
- Dentition * MeSH
- Ectodermal Dysplasia genetics pathology physiopathology MeSH
- Ectodysplasins MeSH
- Phenotype MeSH
- Genetic Linkage MeSH
- Genotype MeSH
- Heterozygote MeSH
- Homozygote MeSH
- Mice, Inbred Strains MeSH
- Humans MeSH
- Mandible MeSH
- Membrane Proteins genetics MeSH
- Disease Models, Animal MeSH
- Mutation * MeSH
- Mice MeSH
- Animals, Newborn MeSH
- Tooth Eruption MeSH
- Tooth pathology MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Male MeSH
- Mice MeSH
- Female MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- EDA protein, human MeSH Browser
- Eda protein, mouse MeSH Browser
- Ectodysplasins MeSH
- Membrane Proteins MeSH
The tabby (Ta) syndrome in mouse is homologous to human anhidrotic ectodermal dysplasia, including defective development of hair, teeth, and glands. To complete the available data on the functional dentition in the Ta mice, we analyzed the mandibular cheek teeth in 261 postnatal specimens arranged in several phenotype/genotype groups: 51 Ta-hemizygous males, 56 Ta-homo/hemizygous females, 64 Ta-heterozygous females, and 40 and 50 wild-type control males and females, respectively. We evaluated tooth number, size, shape and eruption and compared these parameters in the different groups. In any individual group of Ta mice, there was variability mainly in the size and shape of the most mesial tooth and in the tooth patterns. The incidence of a reduction in tooth number in homozygous and hemizygous mice was dependent on the breeding scheme.
References provided by Crossref.org
Patterning by heritage in mouse molar row development
