RTX cytotoxins play an important role in virulence of numerous gram-negative pathogens. Unexpectedly, however, we show here that the RTX proteins of Neisseria meningitidis are dispensable for virulence in the infant rat model of infection.

Laboratory of Molecular Biology of Bacterial Pathogens Institute of Microbiology Czech Academy of Sciences CZ 142 20 Prague 4 Czech Republic

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