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The c-SRC1 gene visualized by in situ hybridization on Xenopus laevis chromosomes

. 2003 ; 103 (1-2) : 169-72.

Language English Country Switzerland Media print

Document type Journal Article, Research Support, Non-U.S. Gov't

Fluorescent in situ hybridization followed by tyramide signal amplification was used to map the site of the c-SRC1 gene on XENOPUS LAEVIS chromosomes. Positive results were obtained with a cDNA probe of about 1 kb. The c-SRC1 gene is located in the subcentromeric region in the long arm of one of the acrocentric chromosomes of the G category (classified according to Graf and Kobel, 1991). The c-SRC1 gene and the XENOPUS major histocompatibility complex (MHC) 1b locus, which consists of 20 tandemly arranged gene copies, are situated on different chromosomes of the G category.

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