The c-SRC1 gene visualized by in situ hybridization on Xenopus laevis chromosomes
Language English Country Switzerland Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
15004482
DOI
10.1159/000076307
PII: 76307
Knihovny.cz E-resources
- MeSH
- Animals, Genetically Modified MeSH
- Genes, src * MeSH
- In Situ Hybridization, Fluorescence MeSH
- Chromosome Mapping MeSH
- Xenopus Proteins genetics MeSH
- Proto-Oncogene Proteins pp60(c-src) genetics MeSH
- Xenopus laevis genetics MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Xenopus Proteins MeSH
- Proto-Oncogene Proteins pp60(c-src) MeSH
Fluorescent in situ hybridization followed by tyramide signal amplification was used to map the site of the c-SRC1 gene on XENOPUS LAEVIS chromosomes. Positive results were obtained with a cDNA probe of about 1 kb. The c-SRC1 gene is located in the subcentromeric region in the long arm of one of the acrocentric chromosomes of the G category (classified according to Graf and Kobel, 1991). The c-SRC1 gene and the XENOPUS major histocompatibility complex (MHC) 1b locus, which consists of 20 tandemly arranged gene copies, are situated on different chromosomes of the G category.
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