Ultrasonography is a generally accepted method for diagnosing both the diffuse and focal (nodal) lesions of the thyroid gland. The main limit of this method is the restricted ability of the human eye to analyse all information included. Moreover, the proportion of subjectivity when evaluating the picture is greater than with other imaging methods. Computer texture analysis in combination with automatic classification may prove a potent tool that could enable--immediately after the standard examination--to assign the finding to a particular type of diffuse disorder, with an accuracy of up to 100 percent. From a variety of procedures, which we have tested until now, the best results were obtained with a combination of spatial, co-occurrence and systematically constructed features, selected by a method that is based on the magnitude of classification error. From several tested ways of classification the Bayes's classificator in combination with the criterion of majority was found to be the best approach.

3 interní klinika 1 LF UK a VFN Praha