Frequency of Gram-negative bacterial pathogens in bloodstream infections and their resistance to antibiotics in the Czech Republic
Language English Country Netherlands Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
15081092
DOI
10.1016/j.ijantimicag.2003.07.021
PII: S0924857903004382
Knihovny.cz E-resources
- MeSH
- Anti-Bacterial Agents pharmacology MeSH
- Drug Resistance, Bacterial * MeSH
- Bacteremia epidemiology microbiology MeSH
- Gram-Negative Bacterial Infections epidemiology microbiology MeSH
- Gram-Negative Bacteria drug effects MeSH
- Cross Infection epidemiology microbiology MeSH
- Humans MeSH
- Microbial Sensitivity Tests MeSH
- Hospitals MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Geographicals
- Czech Republic MeSH
- Names of Substances
- Anti-Bacterial Agents MeSH
A study performed at 12 hospitals in the Czech Republic in 2001 evaluated the Gram-negative bacterial pathogens most frequently associated with bloodstream infections and their susceptibility to a selection of antimicrobial agents. Of 831 Gram-negative strains, the most frequently isolated organisms were Escherichia coli (32%), Klebsiella pneumoniae (24%) and Pseudomonas aeruginosa (10%). E. coli isolates were relatively susceptible to the antibiotics tested, whereas K. pneumoniae were relatively resistant to all agents except meropenem, and P. aeruginosa to all agents except gentamicin and amikacin. Other agents showed variable rates of resistance to penicillins, third-generation cephalosporins, aminoglycosides and ciprofloxacin.
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