Corticosteroid regulation of colonic ion transport during postnatal development: methods for corticosteroid analysis
Language English Country Czech Republic Media print
Document type Journal Article, Research Support, Non-U.S. Gov't, Review
PubMed
15119937
Knihovny.cz E-resources
- MeSH
- Electrophoresis, Capillary MeSH
- Glucocorticoids metabolism MeSH
- Adrenal Cortex Hormones metabolism physiology MeSH
- Ion Transport MeSH
- Colon growth & development metabolism MeSH
- Humans MeSH
- Sodium-Potassium-Exchanging ATPase physiology MeSH
- Chromatography, High Pressure Liquid MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
- Names of Substances
- Glucocorticoids MeSH
- Adrenal Cortex Hormones MeSH
- Sodium-Potassium-Exchanging ATPase MeSH
Many mammalian species including human are immature at birth and undergo major developmental changes during suckling and weaning period. This problem is also conspicuous for the gastrointestinal tract that undergoes abrupt transitions coinciding with birth and weaning. This review deals with the maturation of ion transport functions in colon, the intestinal segment that plays an important role in sodium and potassium absorption and secretion. The purpose of the present review is to summarize the mechanism of sodium and potassium transport pathways and show how these transport processes change postnatally and how hormones, particularly corticosteroids, modify the pattern of development. Finally we describe some of the ways, how to analyze corticosteroid metabolism in target tissue.
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