Hydroxyl groups on the lower rim of calix[4]arene form a circular array of four equivalent hydrogen bonds. The rate constants of reversal of the array in the temperature range of 221-304 K were determined by means of the NMR measurements of quaternary (13)C nuclear spin transverse relaxation dependence on the effective radio frequency field. The flip-flop rate constants are in the range of 1.4 x 10(2)-4.2 x 10(4) s(-1), the activation enthalpy is 36.8 kJ/mol, the activation entropy is -36 J mol(-1) K(-1). This process was found uncorrelated with conformational transition cone-inverted cone, which is about thousand times slower. Molecular tumbling of calix[4]arene measured using (13)C spin relaxation was found isotropic with correlation times lying in the range of 0.1-3 ns and with the activation energy of 21 kJ/mol. In order to assess relaxation of (13)C aromatic nuclei, their principal components of chemical shift tensor were calculated using the density functional theory approach.

Laboratory of NMR Spectroscopy Institute of Chemical Technology Technická 5 CZ 16628 Prague 6 Czech Republic

Citace poskytuje Crossref.org

Synthesis of Monothiacalix[4]arene Using the Fragment Condensation Approach