Secondary pseudohypoaldosteronism in an infant with pyelonephritis
Language English Country Germany Media print
Document type Case Reports, Journal Article
PubMed
15777077
Knihovny.cz E-resources
- MeSH
- Acute Disease MeSH
- Infant MeSH
- Humans MeSH
- Pseudohypoaldosteronism diagnosis etiology MeSH
- Pyelonephritis complications diagnosis MeSH
- Check Tag
- Infant MeSH
- Humans MeSH
- Male MeSH
- Publication type
- Journal Article MeSH
- Case Reports MeSH
BACKGROUND: Urinary tract infections and/or urinary tract anomalies are very frequent among children. Especially in newborns/infants they represent additional factors in the development of secondary pseudohypoaldosteronism. CASE HISTORY: We present an 8-week-old infant who developed hyponatremia and hyperkalemia secondary to acute pyelonephritis. The boy presented with non-specific signs, including poor appetite, lethargy, and hypotonia. An extended evaluation led to the diagnosis of pseudohypoaldosteronism (PHA). PHA was transient and during therapy of pyelonephritis all of abnormal laboratory parameters returned to normal. The patient had vesico-ureteric reflux grade IV. CONCLUSION: Secondary/transient/reversible PHA occurs in patients with immature renal tubular responsiveness to aldosterone due to infancy when they have urinary tract anomalies and/or urinary tract infection. (Tab. 1, Ref. 7.)
