New antimycobacterial S-alkylisothiosemicarbazones
Language English Country United States Media print
Document type Journal Article
PubMed
16681143
DOI
10.1007/bf02931433
Knihovny.cz E-resources
- MeSH
- Aldehydes chemistry pharmacology MeSH
- Anti-Bacterial Agents pharmacology MeSH
- Microbial Sensitivity Tests methods MeSH
- Mycobacterium avium Complex drug effects MeSH
- Mycobacterium avium drug effects MeSH
- Mycobacterium fortuitum drug effects MeSH
- Mycobacterium kansasii drug effects MeSH
- Mycobacterium tuberculosis drug effects MeSH
- Nontuberculous Mycobacteria classification drug effects MeSH
- Thiosemicarbazones chemistry pharmacology MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Aldehydes MeSH
- Anti-Bacterial Agents MeSH
- Thiosemicarbazones MeSH
In connection with a systematic study of antimycobacterial agents against potentially pathogenic strains the series of 12 S-alkylisothiosemicarbazones was evaluated for in vitro antimycobacterial activity against Mycobacterium tuberculosis, M. kansasii, M. fortuitum, two strains of M. intracellulare and three strains of M. avium. Quinoline-4-carbaldehyde-S-hexyl-isothiohydrazone was found to be more active against potentially pathogenic strains than isoniazide.
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