Adjacent location of the bac gene and two-component regulatory system genes within the putative Streptococcus agalactiae pathogenicity island
Jazyk angličtina Země Spojené státy americké Médium print
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
17004655
DOI
10.1007/bf02932127
Knihovny.cz E-zdroje
- MeSH
- antigeny bakteriální genetika MeSH
- bakteriální proteiny genetika MeSH
- DNA bakterií analýza MeSH
- faktory virulence genetika MeSH
- genomové ostrovy genetika MeSH
- lidé MeSH
- molekulární sekvence - údaje MeSH
- regulace genové exprese u bakterií genetika MeSH
- sekvenční homologie nukleových kyselin MeSH
- Streptococcus agalactiae * genetika patogenita MeSH
- Streptococcus pneumoniae genetika MeSH
- těhotenství MeSH
- Check Tag
- lidé MeSH
- těhotenství MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Názvy látek
- antigeny bakteriální MeSH
- bakteriální proteiny MeSH
- DNA bakterií MeSH
- faktory virulence MeSH
A chromosomal DNA fragment of 8992 bp in size that has not been previously identified in Streptococcus agalactiae, was cloned and sequenced from strain 98-D60C. In particular, this 8992-bp fragment contained genes homologous to the sensor histidine kinase gene and the DNA-binding response-regulator gene of Streptococcus pneumoniae, and S. agalactiae bac gene. Structural and genetic features of the 8992-bp fragment were highly similar to those specific for bacterial pathogenicity islands. Analysis of epidemiologically unrelated S. agalactiae strains revealed that this fragment was present only in bac gene-positive strains. The possible origin of the 8992-bp fragment in S. agalactiae and its significance for molecular mechanisms of "bacteria-host" interactions are discussed.
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GENBANK
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