Body indices and basic vital signs in Helicobacter pylori positive and negative persons
Language English Country Netherlands Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
17195049
PubMed Central
PMC2799154
DOI
10.1007/s10654-006-9090-1
Knihovny.cz E-resources
- MeSH
- Breath Tests MeSH
- Child MeSH
- Adult MeSH
- Helicobacter pylori * MeSH
- Hypertension complications MeSH
- Helicobacter Infections complications epidemiology physiopathology MeSH
- Blood Pressure * MeSH
- Middle Aged MeSH
- Humans MeSH
- Adolescent MeSH
- Obesity complications MeSH
- Child, Preschool MeSH
- Aged, 80 and over MeSH
- Aged MeSH
- Body Weight * MeSH
- Body Height * MeSH
- Age Distribution MeSH
- Check Tag
- Child MeSH
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Adolescent MeSH
- Male MeSH
- Child, Preschool MeSH
- Aged, 80 and over MeSH
- Aged MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
It has been hypothesized that Helicobacter pylori (Hp) infection may contribute to reduced stature, risk of hypertension or obesity. The aim was to evaluate body indices in Hp positive and negative persons. A total of 2436 subjects (4-100 years old) were tested for Hp status by (13)C-urea breath test. Data on height and weight were collected for 84%, and blood pressure for 80% of the study subjects. The prevalence of Hp infection was 41.6%. The odds ratio for a 10-year increase in age was 1.21 (95% CI 1.17-1.25, p-value <0.001). Statistically significant negative association of Hp positivity with body height was most pronounced in the younger age groups, while a positive association of Hp positivity with body mass index was only seen in those aged 15+ years. There was a negative effect of Hp positivity on systolic and diastolic blood pressure in subjects below 25 and a relatively strong positive effect on blood pressure in subjects over 65 years. Residual confounding by social characteristics as a possible explanation for the associations of Hp positivity with height and blood pressure cannot be excluded. Unmeasured factors related to social and family environment may cause the apparent association between Hp positivity and children's growth and blood pressure.
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